| Date | Home | Frames | Points | | Points | Frames | Away |
| 22/11/2021 | Brown, David (19) - Walkers B | 0 | 0 | v | 0 | 0 | Ormesher, Danny (29) - Kings Club C |
| 22/11/2021 | Bate, Phil (-11) - Woolston A | 0 | 0 | v | 0 | 0 | Williams, Kev (23) - Kings Club B |
| 22/11/2021 | Frederick, Gary (-12) - Alford B | 0 | 0 | v | 0 | 0 | Rathbone, John (17) - The Hatter |
| 22/11/2021 | Leathem, Mark (15) - Woolston A | 0 | 0 | v | 0 | 0 | Taylor, Alan (-2) - Irlam Catholic |
| 22/11/2021 | Dolly, Stephen (11) - Kings Club A | 0 | 0 | v | 0 | 0 | Owen, Keith (23) - Monks A |
| 22/11/2021 | O'Rourke, John (17) - G.E.S.M. B | 0 | 0 | v | 0 | 0 | Babington, Mike (24) - Alford A |
| 22/11/2021 | McJay, Mitch (25) - Kings Club A | 0 | 0 | v | 0 | 0 | Horton, Harry (8) - Alford B |
| 22/11/2021 | Warren, John (2) - The Grange | 0 | 0 | v | 0 | 0 | Bamber, Harry (38) - Kings Club A |
| 22/11/2021 | Babington, Brian (25) - Alford A | 0 | 0 | v | 0 | 0 | Garnett, Stewart (10) - G.E.S.M. A |
| 22/11/2021 | Cook, Dexter (2) - Monks A | 0 | 0 | v | 0 | 0 | Bonehill, Dave (43) - Woolston A |
| 22/11/2021 | Jones, Nick (13) - Irlam Catholic | 0 | 0 | v | 0 | 0 | Dean, Paul (-26) - G.E.S.M. A |
| 22/11/2021 | Fenney, Glyn (16) - The Hatter | 0 | 0 | v | 0 | 0 | Withers, Mike (16) - Kings Club C |
| 22/11/2021 | Wisedale, Pat (-10) - G.E.S.M. A | 0 | 0 | v | 0 | 0 | Small, John (15) - Warrington Cons B |
| 22/11/2021 | Brereton, Jason (12) - St Benedicts A | 0 | 0 | v | 0 | 0 | Chisnall, Lee (22) - The Hatter |
| 22/11/2021 | Lawton, Richard (36) - Warrington Cons B | 0 | 0 | v | 0 | 0 | Horobin, Scott (5) - Woolston A |
| 22/11/2021 | Whittaker, Steve (24) - The Hatter | 0 | 0 | v | 0 | 0 | Delaney, Mike (15) - Monks A |
| 22/11/2021 | Veldhoven, Keith (-12) - Irlam Steel | 0 | 0 | v | 0 | 0 | Whittaker, Tyler (22) - Kings Club A |