| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 1 | 30/09/2021 | Away | | | Lost | 75 | v | 103 | Sweeney, Ian (24) | Bridgewater A | | |
| Week 2 | 07/10/2021 | Home | | | Won | 83 | v | 57 | Stapley, Arthur (6) | Irlam Catholic | | |
| Week 6 | 04/11/2021 | Home | | | Won | 68 | v | 60 | Wilkinson, Mark (-6) | Woolston A | | |
| Week 8 | 18/11/2021 | Home | | | Lost | 68 | v | 88 | Herriot, Glen (25) | Penketh Cons B | | |
| Week 9 | 25/11/2021 | Away | | | Lost | 70 | v | 83 | Owen, Mike (10) | Irlam Steel | | |
| Week 12 | 16/12/2021 | Away | | | Won | 84 | v | 54 | Chambers, Lee (27) | G.E.S.M. A | | |
| Week 13 | 06/01/2022 | Home | | | Lost | 41 | v | 81 | Cheng, Nick (4) | Kings Club C | | |
| Week 14 | 13/01/2022 | Home | | | Lost | 81 | v | 82 | Evans, Rob (20) | Bridgewater A | | |
| Week 16 | 27/01/2022 | Home | | | Won | 60 | v | 51 | Warren, John (2) | The Grange | | |
| Week 17 | 03/02/2022 | Away | | | Lost | 67 | v | 81 | Aspinall, Wayne (11) | Eagle Sports | | |
| Week 19 | 17/02/2022 | Away | | | Won | 86 | v | 76 | Bonehill, Dave (43) | Woolston A | | |
| Week 20 | 24/02/2022 | Home | | | Lost | 64 | v | 71 | Shaw, Danny (15) | Kings Club A | | |
| Week 21 | 03/03/2022 | Away | | | Lost | 47 | v | 73 | Giblin, Chris (19) | Penketh Cons B | | |
| Week 22 | 10/03/2022 | Home | | | Won | 109 | v | 79 | Carey, Daryl (28) | Irlam Steel | | |
| Week 23 | 17/03/2022 | Away | | | Lost | 55 | v | 87 | Taylor, Mark (17) | Alford D | | |
| Week 24 | 24/03/2022 | Away | | | Lost | 48 | v | 103 | Ure , Chris (32) | Monks A | | |
| Week 25 | 31/03/2022 | Home | | | Won | 69 | v | 55 | Barton, John (-1) | G.E.S.M. A | 1 | 35 |
| Week 26 | 21/04/2022 | Away | | | Won | 83 | v | 32 | Withers, Mike (16) | Kings Club C | | |
|